Model:
Name: Markevich_2004_MAPK_phosphoRandomElementary
Description:
Keywords:
References:
J Cell Biol 2004 Feb;164(3):353-9.Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades. Markevich NI, Hoek JB, Kholodenko BN. Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, 1020 Locust St., Philadelphia, PA 19107, USA.
Le Novère N., Bornstein B., Broicher A., Courtot M., Donizelli M., Dharuri H., Li L., Sauro H., Schilstra M., Shapiro B., Snoep J.L., Hucka M.(2006) BioModels Database: A Free, Centralized Database of Curated, Published, Quantitative Kinetic Models of Biochemical and Cellular Systems. Nucleic Acids Res., 34: D689-D691.
Comment:
Reactants:
M
MpY
MpT
Mpp
MEKc
MKP3c
MpY$MEK
MpT$MEK
M$MEKY
M$MEKT
Mpp$MKP3
MpY$MKP3
MpT$MKP3Y
MpT$MKP3T
M$MKP3T
M$MKP3Y
Reactions:
M$MEKY Disassociation
MpY$MEK Disassociation
M$MEKT Disassociation
MpT$MEK Disassociation
Mpp$MKP3 to MpT$MKP3Y
MpT$MKP3T to M$MKP3T
MpY$MKP3 to M$MKP3Y
M$MEKY complex formation
MpY$MEK complex formation
M$MEKT complex formation
MpT$MEKc complex formation
Mpp$MKP3 complex formation
MpY$MKP3 complex formation
MpT$MKP3 complex formation
MpT$MKP3Y Disassociation
M$MKP3T Disassociation
M$MKP3Y Disassociation
M$MEKY complex formation
MpY$MEK complex formation
M$MEKT complex formation
MpT$MEKc complex formation
M$MEKY Disassociation
MpY$MEK Disassociation
M$MEKT Disassociation
MpT$MEK Disassociation
Mpp$MKP3 complex formation
MpY$MKP3 complex formation
MpT$MKP3 complex formation
Mpp$MKP3 to MpT$MKP3Y
MpT$MKP3T to M$MKP3T
MpY$MKP3 to M$MKP3Y
MpT$MKP3Y Disassociation
M$MKP3T Disassociation
M$MKP3Y Disassociation
