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Model:
Name:
Kofahl_2004_Yeast_Pheromone_Pathway
Description:
Keywords:
References:
Kofahl B, Klipp E. Modelling the dynamics of the yeast pheromone pathway. Yeast. 2004 Jul 30;21(10):831-50.
Comment:
Reactants:
a
Ste5
Ste11
Ste7
Fus3
Ste2
Ste12
Ste20
Cdc28
Far1
Bar1
Bar1active
Bar1ex
Ste2active
Gbg
GaGTP
GaGDP
Sst2active
Fus3pp
Ste12active
Far1pp
Far1Ubiq
Gbg$GaGDP
Ste5$Ste11
Ste7$Fus3
Ste5$Ste11$Ste7$Fus3
Gbg$Ste5$Ste11$Ste7$Fus3
Ste20$Gbg$Ste5$Ste11$Ste7$Fus3
Ste20$Gbg$Ste5$Ste11ppp$Ste7$Fus3
Ste20$Gbg$Ste5$Ste11ppp$Ste7pp$Fus3
Ste20$Gbg$Ste5$Ste11ppp$Ste7pp$Fus3pp
Ste20$Gbg$Ste5p$Ste11ppp$Ste7pp$Fus3pp
Ste20$Gbg$Ste5p$Ste11ppp$Ste7pp
Ste20$Gbg$Ste5p$Ste11ppp$Ste7pp$Fus3
Far1pp$Gbg
Far1pp$Cdc28
Reactions:
Far1 activation Math
Ste2active downregulation Math
Ste2 degradation Math
Sst2active degradation Math
Ste5$Ste11$Ste7$Fus3 Decomposition Math
Ste20$Gbg$Ste5$Ste11$Ste7$Fus3 Decomposition Math
Ste20$Gbg$Ste5$Ste11ppp$Ste7$Fus3 Decomposition Math
Ste20$Gbg$Ste5$Ste11ppp$Ste7pp$Fus3 Decomposition Math
Ste20$Gbg$Ste5$Ste11ppp$Ste7$Fus3pp Decomposition Math
Fus3pp Release Math
Active Scaffold Decomposition Math
Ste5$Ste11 Ste7$Fus3 Composition Math
Gbg GaGDP Composition Math
Ste2 inactivation Math
Gbg activation Math
GaGTP inactivation Math
Ste11 activation Math
Ste7 activation Math
Fus3 activation Math
Ste5 P Math
Fus3 activation with active scaffold Math
Fus3pp Dephosphorylation Math
Ste12 activation Math
Ste12 activation reversed Math
Bar1 inactivation Math
Bar1active extracellular Math
Far1 inactivation Math
Ste5 Ste11 Composition Math
Ste7 Fus3 Composition Math
Gbg Ste5 scaffolding complex Math
Ste20 Gbg Ste5 scaffolding complex Math
Fus3 Binds/Released complex Math
Far1pp complexed with Gbg Math
Far1pp complexed with Cdc28 Math
a pheromone degradation Math
Ste2 activation Math
GaGTP catalyzed inactivation Math
Bar1 activation Math
Far1 Ubiquitination Math
Sst2activation Math
Sst2activation Bio
Ste5 Ste11 Composition Bio
Ste7 Fus3 Composition Bio
Gbg Ste5 scaffolding complex Bio
Ste20 Gbg Ste5 scaffolding complex Bio
Fus3 Binds/Released Bio
Far1pp complexed with Gbg Bio
Far1pp complexed with Cdc28 Bio
Ste2active downregulation Bio
Ste2 degradation Bio
Sst2active degradation Bio
Ste5$Ste11$Ste7$Fus3 Decomposition Bio
Ste20$Gbg$Ste5$Ste11$Ste7$Fus3 Decomposition Bio
Ste20$Gbg$Ste5$Ste11ppp$Ste7$Fus3 Decomposition Bio
Ste20$Gbg$Ste5$Ste11ppp$Ste7pp$Fus3 Decomposition Bio
Ste20$Gbg$Ste5$Ste11ppp$Ste7pp$Fus3pp Decomposition Bio
Fus3pp Release Bio
Active Scaffold Decomposition Bio
Ste5$Ste11 Ste7$Fus3 Composition Bio
Gbg GaGDP Composition Bio
Ste2 inactivation Bio
Gbg activation Bio
GaGTP inactivation Bio
Ste11 activation Bio
Ste7 activation Bio
Fus3 activation Bio
Ste5 P Bio
Fus3 activation with active scaffold Bio
Fus3pp Dephosphorylation Bio
Ste12 activation Bio
Bar1 inactivation Bio
Bar1active extracellular Bio
Far1 activation Bio
Far1 inactivation Bio
a pheromone degradation Bio
Ste2 activation Bio
GaGTP catalyzed inactivation Bio
Bar1 activation Bio
Far1 Ubiquitination Bio