Model:

Name: Huang_1996_MAPK
Description:
Keywords:
References:

Proc Natl Acad Sci U S A 1996 Sep;93(19):10078-83. Ultrasensitivity in the mitogen-activated protein kinase cascade. Huang CY, Ferrell JE. Department of Molecular Pharmacology, Stanford University School of Medicine, CA 94305-5332, USA.

Le Novère N., Bornstein B., Broicher A., Courtot M., Donizelli M., Dharuri H., Li L., Sauro H., Schilstra M., Shapiro B., Snoep J.L., Hucka M.(2006) BioModels Database: A Free, Centralized Database of Curated, Published, Quantitative Kinetic Models of Biochemical and Cellular Systems. Nucleic Acids Res., 34: D689-D691.

Comment:

Reactants:

E1

E2

KKK

KKKp

KK

KKp

KKpp

K

Kp

Kpp

KPase

KKPase

Reactions:

KKK Phosphorylation Math

KK Phosphorylation Math

KKKp Dephosphorylation Math

KKp Dephosphorylation Math

KKp Phosphorylation Math

KKpp Dephosphorylation Math

K Phosphorylation Math

Kp Phosphorylation Math

Kpp Dephosphorylation Math

Kp Dephosphorylation Math

KKK Phosphorylation

KKKp Dephosphorylation

KK Phosphorylation

KKp Dephosphorylation

KKp Phosphorylation

KKpp Dephosphorylation

K Phosphorylation

Kp Dephosphorylation

Kp Phosphorylation

Kpp Dephosphorylation